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How a researcher divides it depends entirely on reconstitution

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10.3892/mco.2018.1557 [DOI] [PMC free article] [PubMed] [Google Scholar] 23.Cruciani RA, Dvorkin E, Homel P, Culliney B, Malamud S, Shaiova L, et al

This assembly subsequently activates caspase-1 through CARD-CARD interactions, thereby completing the NLRP3 inflammasome, which drives immune and inflammatory responses by facilitating the maturation of IL-1 and IL-18 and inducing pyroptosis (62) ( Figure 8 )