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Although brain uptake is modest early on, tracer binding in motor cortex and brainstem increases as disease advances, mirroring human ALS neuroinflammation and expanding diagnostic reach to neuromuscular involvement (142, 146, 147)

There is no randomized controlled trial none of KLOW, GLOW, or Wolverine as a fixed combination

8 No thyroid dysfunction was detected after 24 weeks (mean follow-up period: 317 210 days in the pembrolizumab group and 346 362 days in the nivolumab group)