Results Regression analysis showed that: a) age ( P = 0.001), gender ( P = 0.03), lower estimated glomerular filtration rate (eGFR, P = 0.08), body mass index ( P = 0.008), treatment with beta-blockers ( P = 0.03), homocysteine ( P = 0.02), and glutamylcysteine ( P = 0.003) were independently associated with higher ADMA concentrations
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Another metabolomics study aimed to discriminate colorectal adenoma, colorectal cancer, and healthy subjects [55]
Lastly, melatonin upregulates s Nrf2, an antioxidant protein that promotes ROS scavenging and elimination to facilitate protection against NLRP3 inflammasome activity through ROS scavenging and elimination mediated by Nrf2 (102)