tirzepatide surpass 4 SURPASS-4 trial: slows rate of eGFR decline and reduces UACR in T2DM patients Tirzepatide superior to insulin glargine

Effects on GLP-1 specifically varied widely between studies, likely due to different bacterial strains used

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doi:10.1056/NEJMoa1615692 Although not directly focused on semaglutide, this study compared the long-acting insulin analog degludec with glargine in patients with type 2 diabetes and might provide insights into blood pressure effects of different glucose-lowering therapies

Comprender los diferentes perfiles de efectos secundarios de estos medicamentos es fundamental para tomar una decisin informada