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Tirzepatide is a once-weekly injectable medication that activates both GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptors a dual mechanism that distinguishes it from semaglutide, which activates only GLP-1

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15,16 Meta-analyses have demonstrated that these agents are associated with reductions in AHI and improvements in sleep-related outcomes in patients with obesity-related OSA

While the percentage of granulocytes decreased significantly below the initial level until 4 h pi , the percentage of lymphocytes increased to a significantly higher level during the same period