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GLP-1 (glucagon-like peptide-1) receptor agonists - such as semaglutide - work by mimicking a naturally occurring hormone that helps regulate appetite, slows stomach emptying, and signals the brain to reduce hunger

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55,56 Furthermore, a trial conducted in patients without T2DM indicated that liraglutide 3 mg daily provided benefits comparable to those of structured lifestyle changes in improving liver enzymes, insulin resistance, and weight, which are considered effective and fundamental measures for managing and improving MASLD/MASH