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Our findings from this admittedly small study are, nevertheless, so promising for newly diagnosed Type 1 diabetes patients that we are now absolutely focused on pursuing a larger study for a longer period of time, says Paresh Dandona, MD, PhD, SUNY Distinguished Professor in the Department of Medicine, former chief of the Division of Endocrinology in the Jacobs School of Medicine and Biomedical Sciences at UB, a physician with UBMD Internal Medicine and senior author on the paper

Not everyone will have this side effect, but for some, the interplay between hormonal balance and body weight shifts can be a factor that contributes to period irregularity

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This issue has been attributed to the mode of action of these antagonists: those blocking CAP-, proton-, and heat-induced TRPV1 activation result in hyperthermia, whereas those sparing proton-induced activation do not lead to hyperthermia 33,35