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Key Takeaway: The form of the nutrient (reduced) is important, but the delivery system (how it gets into your blood) is the most critical factor for seeing actual results

Cmara NO, Iseki K, Kramer H, et al

Topical glutathione formulations also exist but are widely considered the least effective delivery method because glutathione molecules are too large to penetrate the skin effectively in their intact form

364:127-135 [PMC free article: PMC3030449] [PubMed: 21226578] 91