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Ipamorelin signaling has been hypothesized to involve phospholipase C pathways and intracellular calcium mobilization, representing a mechanistic route different from that of Sermorelin

( 10.1097/01.gco.0000192994.37965.c6) [DOI] [PubMed] [Google Scholar] Tsounapi P, Honda M, Dimitriadis F, Koukos S, Hikita K, Zachariou A, Sofikitis N, Takenaka A.2018

If you have thyroid issues, you do not necessarily have to miss out on these benefits, but you do need to be "thyroid-aware." By focusing on optimisation, monitoring your markers through a structured approach, and maintaining an open dialogue with your GP, you can navigate this journey safely