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8 Glutathione (GSH) is a crucial intracellular antioxidant, a tripeptide (-glutamyl-cysteinyl-glycine) (Figure 1), and plays a key role in maintaining cellular redox balance

A key trigger for ferroptosis is the dysregulation of Fe 2+ metabolism, and under physiological conditions, intracellular iron homeostasis is tightly maintained to support normal functions

In the future, there is still a need for systematic in-depth (m6A) RNA modification mechanisms and metabolic function-related studies

While this preliminary research is intriguing, randomized controlled trials are necessary to determine whether glucosamine supplementation can reliably improve outcomes for those with IBD