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169,379 However, participants in the metformin group remained on the drug for up to 15 years, while long-term adherence to the lifestyle changes tapered off over time

Too Much Stress Stress influences weight gain through hormonal fluctuations, such as increased cortisol levels, which promote fat storage and trigger cravings for high-calorie foods

This helps reduce hunger, curb cravings, and promote a feeling of satiety

In spite of COVID-19 pandemic, the patient achieved tight glycemic control (HbA1c 41 mmol/mol) with non-severe hypoglycemic events in the face of significant body weight (BW) increase (+ 13 kg vs baseline)