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Inoue-Yamauchi et al., 2018

Passive Cooling: Ice Packs and Insulated Bags Best For : Short trips (under 12 hours) or situations with regular ice access How They Work : Insulated bags with pre-frozen gel packs maintain cool temperatures without electricity

Risk-Benefit Assessment : The potential benefits must be carefully weighed against known and unknown risks, particularly given the limited long-term safety data in adolescents

Dyspnea is the most common presenting symptom, often prompting initial medical consultation, while chronic dry cough and velcro-like crackles on auscultation are also characteristic clinical features [1, 2]