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Step 2: Administer Daily Subcutaneous Injections During the 14-Day Loading Phase The clinical photoprotection protocol uses 0.16mg/kg body weight administered subcutaneously once daily for 14 consecutive days to achieve baseline eumelanin saturation

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Weight-based dosing considerations While flat doses dominate clinical trials, weight-based adjustments may optimize individual protocols

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10.1146/annurev-pharmtox-011112-140320 121 Mahmoud MoustafaE.RashedE

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