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BPC 157 antagonized portal/caval hypertension (caval portal hypertension), and aortal hypotension, refractory ascites and thrombosis (portal vein tributaries, inferior vena cava, hepatic and coronary arteries), pathology of the lungs (severe capillary congestion) and liver (dilated central veins and terminal portal venules), intestine hemorrhagic lesions (substantial capillary congestion, submucosal edema and architecture loss), increased liver and spleen weight serum and enzymes values, NO- and MDA-levels in the liver

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This ecological disruption is typically characterized by the reduction of beneficial bacteria such as Lactobacillus and Bifidobacterium , which play a protective role against pathogenic organisms [24, 36, 81]

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