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Pitfalls and limitations in translation from biomarker discovery to clinical utility in predictive and personalised medicine

J Clin Investig 126(2):695705 Ganesan P et al (2015) Recent trends in the development of nanophytobioactive compounds and delivery systems for their possible role in reducing oxidative stress in Parkinsons disease models

It is a complex network of interlocking genetic feedback loops involving clock genes (Clock, Bmal1), period genes (Per1, Per2, Per3), and cryptochrome genes (Cry1, Cry2)

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