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doi: 10.1016/j.cmet.2019.06.005 103

Although the mechanism of action of DMF is not completely understood in MS, DMF is thought to be an immunomodulatory therapy that decreases inflammatory T cells via increasing nuclear factor erythroid 2related factor 2 (Nrf2) and glutathione (GSH), the cell's regulators of anti-oxidant response (Figure 4) (165)