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[4] Endogenous GLP-1 is rapidly degraded primarily by dipeptidyl peptidase-4 (DPP-4), but also neutral endopeptidase 24.11 and renal clearance, resulting in a half-life of approximately 2 minutes

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Amyotrophic lateral sclerosis Amyotrophic lateral sclerosis (ALS) is a fatal progressive neurological disorder characterized by muscle paralysis caused by the degeneration of motor neurons in the brain, brainstem and spinal cord

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