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Today, there is no scientific evidence that this happens, but a related drug in the class, tirzepatide (Mounjaro, Zepbound), carries warnings on its FDA labels that it may reduce the efficacy of oral hormonal contraceptives due to delayed gastric emptying. Patients are advised to switch to a non-oral form of contraception or to add a barrier method, such as condoms

Limit late-night snacking and eating too late at night

This is why baseline blood pressure monitoring before starting semaglutide becomes essential for patients with existing hypertension