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Neurology 81(13):11591165 Rosser DA et al (2003) How sensitive to clinical change are ETDRS logMAR visual acuity measurements

52A , B98B102 (1997)

[107] Administration timing may affect the tolerability and efficacy of mirtazapine therapy, with evening dosing often preferred due to the medications sedating properties

By doing so, you bypass the digestive system, which can sometimes hinder absorption