ROS readout is shown in the y-axis as percentage, with H 2 O 2 150uM group being 100 percent
Storage and Handling Storage temperature: Store sealed in a cool, dry location away from direct light Long-term storage: Room temperature (15-25C) in original sealed bottle, or refrigerated at 2-8C for extended storage Light exposure: Protect from direct sunlight and prolonged light exposure Container integrity: Inspect seal before each use Avoid: Freezing, extreme temperatures, or moisture exposure Quality Standards Mile High Compounds maintains a rigorous quality control framework across all research compounds
SIRT1 targets over 100 different proteins involved in metabolism, stress responses, and longevity pathways, including the tumor suppressor p53, the transcriptional coactivator PGC-1, and the DNA repair protein Ku70. Through deacetylation of PGC-1, SIRT1 promotes mitochondrial biogenesis and oxidative metabolism, while deacetylation of p53 reduces apoptotic responses to mild stress, promoting cellular survival and longevity
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