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Patients with underlying medical conditions, especially kidney or liver disease, should use it under medical supervision as dosage adjustments might be necessary

The chemical composition of the chyme entering the duodenum also affects the rate of gastric emptying, and influences hormone secretion

Heerspink HJL, Apperloo E, Davies M, Dicker D, Kandler K, Rosenstock J, et al

BMI of 30 or higher (obesity) BMI of 27 or higher with a weight-related condition (hypertension, type 2 diabetes, high cholesterol, sleep apnea) Have tried diet and exercise without sustained results Are not pregnant, nursing, or planning pregnancy Have no personal or family history of medullary thyroid cancer or MEN2 syndrome Not sure if you qualify