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BPC 157 therapy (intragastric or abdominal bath, 10 g/kg and 10 ng/kg dosages), using a previously described protocol, could alleviate suprahepatic occlusion of the inferior caval vein, as model of the BCS in rats, activating bypassing pathways
This allows the toxic backlog of methylmalonyl-CoA to be successfully converted into succinyl-CoA, which then flows smoothly into the Krebs cycle
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