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5a), approved for the treatment of amyotrophic lateral sclerosis, increases ROS levels by multiple mechanisms, including decreasing LDH-A and NAD + levels to increase oxidative stress, as well as interfering with the xCT antiporter to block the cystineglutamate pump

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Patients experiencing sudden vision changes should seek immediate medical attention and should not stop taking prescribed medication without consulting their healthcare provider, as other eye conditions such as glaucoma, diabetic retinopathy, or unrelated vascular disorders may also affect vision