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Key Features and Benefits Preservative Addition: Contains bacteriostatic agents to inhibit bacterial growth, enhancing its shelf life

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The principle of senolytic approach is to target antiapoptotic pathways by inhibiting or activating proteins that regulate apoptosis resistance 112

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Pre-specified outcomes The primary outcome was defined as the annual rate of acute healthcare utilization (number of events per year of follow-up): calculated as the sum of urgent care visits, Emergency Department visits, and hospitalizations divided by the duration of follow-up

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