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Contact your healthcare provider immediately if you experience symptoms such as: Unusual bleeding or spotting Signs of blood clots, such as leg pain, swelling, or chest pain Severe headaches or vision changes Muscle weakness or irregular heartbeat Any unexpected side effects after starting a new medication or supplement Prompt evaluation can prevent serious complications and ensure your contraceptive method remains effective and safe

Paula Greaves and Wellstar Cobb President Eliese Bernard

Abbreviations CAD: Coronary artery disease EAT: Epicardial adipose tissue HF: Heart failure SGLT2i: Sodium-glucose cotransporter-2 inhibitors T2DM: Type 2 diabetes CV: Cardiovascular MACE: Major adverse cardiovascular events SAT: Subcutaneous adipose tissue CFR: Coronary flow reserve WAT: White adipose tissue BAT: Brown adipose tissue UCP 1: Uncoupling protein 1 FGF-21: Fibroblast growth factor 21 PCOS: Polycystic ovary syndrome SOD2: Enzyme superoxide dismutase PRDM16: PR domain-containing 16 FFAs: Free fatty acids IL-6: Interleukin-6 TNF-r1: Tumor necrosis factor receptor-1 TNF-: Tumor necrosis factor- PAI-1: Plasminogen activator inhibitor-1 References Zinman B, et al

On the other hand, GHR ablation in the entire brain was expected to increase GH secretion due to impaired GH negative feedback