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It is being studied in clinical trials for obesity and overweight with weight-related conditions, type 2 diabetes, knee osteoarthritis pain, moderate-to-severe obstructive sleep apnea, chronic low back pain, cardiovascular and renal outcomes, and metabolic dysfunction-associated steatotic liver disease

Pricing and availability vary substantially by country, and a few destinations Canada, several EU countries have considerably lower out-of-pocket prices than the US for the same molecules

10.1038/ncb0311-184 120 TadaY.SpoelS

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