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MAMs are essential for the regulation of the neuronal Ca 2+ concentration via the SERCA, the ER channels inositol 1,4,5-trisphosphate receptors, the glucose-regulated protein 75, the MCU, and the voltage-dependent anion channel (VDAC) [61]

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Order-level profiles (Figure S1C) indicated that the VPA-ASD model was dominated by Clostridiales and Desulfovibrionales, with elevated Erysipelotrichales and reduced Bacteroidales and Verrucomicrobiales

A systematic review and meta-analysis of serum phosphorous levels and the progression of CKD showed an association between elevated phosphorous levels and an increased risk of kidney failure, along with higher mortality in patients with CKD