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Our body naturally makes L-Carnitine mainly in the liver and kidneys, using amino acids like lysine and methionine, along with vitamin C, and a few more micronutrients

Methods We used a subset of Truveta Data to identify patients aged 18 years or older with overweight or obesity (defined as BMI over 27) and at least one medication dispense (i.e., prescription filled at a pharmacy) for a GLP-1 RA between January 2025 and July 2025

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Patients should immediately discontinue tirzepatide and seek urgent medical care for severe, persistent abdominal pain radiating to the back, particularly if accompanied by nausea and vomiting