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The HMB can be absorbed across ruminal, omasal, and abomasal epithelium (McCollum et al., 2000), being converted to Met in peripheral tissues (mainly nonhepatic tissues) after absorption (Lobley et al., 2006a)

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To date, numerous ferroptosis-inducing agents have been identified and sanctioned, with the aim of surmounting the limitations of conventional chemotherapeutic agents that trigger apoptosis (Hassannia et al., 2019b