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Description

Sorting nexin 25 (SNX25) in dermal macrophages inhibits the ubiquitination and proteasomal degradation of NRF2, thereby regulating the production of NGF in dermal macrophages

Slattery JT, Nelson SD, Thummel KE

However, these cells are highly sensitive to their environment, and elevated oxidative stress can physically trigger them to degranulate inappropriately

Kyla et al