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Semaglutide is not indicated for type 1 diabetes

Physiol Rev 78:133

Novo Nordisk) was also FDA approved in 2019 as the first oral GLP-1 receptor agonist for T2D

3.1.1 Impact of ROS on cellular function and atherosclerosis Elevated ROS can induce endothelial cell dysfunction or death, disrupting the vascular barrier and leading to vasoconstrictive and vasodilatory dysfunction, vascular smooth muscle cell proliferation and migration, inflammatory responses, and thrombosisprocesses intimately associated with various cardiovascular disorders, including atherosclerosis, hypertension, and CHD (31)