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Importantly, semaglutide should be discontinued at least 2 months before a planned pregnancy and is not recommended during pregnancy or breastfeeding

Excessive drowsiness, prolonged headaches, or other persistent side effects may indicate individual sensitivity requiring dose reduction or timing adjustments

Fourth, valproylcarnitine inhibits the membrane carnitine transporter, thereby decreasing the transport of extracellular carnitine into the cell and the mitochondria

Neurology 65 , 18101812 (2005)