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Hepatic Safety Summary No hepatic safety signal has been identified across the orforglipron clinical program encompassing thousands of participants

The most common early clinical signs observed in cats with liver disease are anorexia, lethargy, and weight loss, which are signs present in many (if not most!) feline diseases.2, 15 Because these early indicators of disease do not point specifically toward liver disease, a delay in diagnosis will occur unless the clinician carefully considers all possibilities and performs other tests to further evaluate the situation