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We first studied angiogenesis during depilation-induced, synchronized adult hair cycling (22) by computer-assisted morphometric analyses of back skin sections stained for CD31, an endothelial junction molecule (29)

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59,60 Specific genes implicated include vascular endothelial growth factor (VEGF), neurotrophic receptor tyrosine kinase 1, sodium voltage-gated channel alpha subunit 2 (SCN2A), angiotensin-converting enzyme, and methylenetetrahydrofolate reductase, with polymorphisms associated with increased DN susceptibility