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The morphological basis for the evolution of acute pancreatitis into chronic pancreatitis

2,11 But if a patient cannot tolerate escalation and is benefiting at a low dose, I would rather keep her on a tolerable dose than lose her from treatment altogether

Additionally, a chromosome aberration assay using human peripheral blood lymphocytes exposed to the extract at concentrations of 0.25, 0.5, 1, and 2 mg/ml and in vivo micronucleus test in mammalian erythrocyte cells that received doses of 500, 1,000, and 2,000 mg/kg also showed that the extract had no inhibitory effects on the mitotic index, the formation of micronuclei, or cell proliferation, and did not induce chromosomal abnormalities

den Besten G, van Eunen K, Groen AK, Venema K, Reijngoud DJ, Bakker BM