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December 2024 The U.S

availability on the NHS is subject to local commissioning decisions and specific eligibility criteria, and it is not broadly recommended by NICE for routine adult weight management Orlistat a lipase inhibitor available on prescription or over the counter (as Alli) for weight loss support, in line with NICE guidance Structured NHS weight management programmes, including referral to specialist tier 3 or tier 4 services where clinically appropriate For concerns about growth hormone deficiency , a GP can refer patients to an endocrinologist for formal assessment

It is mainly involved in energy metabolism, especially the transport of fatty acids

Nausea, vomiting, and diarrhea are common side effects, but clinical trials reveal that severe gastrointestinal adverse reactions affect 4.1% of WEGOVY-injection patients, while only 0.9% of placebo groups experience these issues