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Hargreaves M, Spriet LL

KPV also shifts macrophage polarization from M1 (pro-inflammatory, destructive) to M2 (reparative) without suppressing overall immune function

Rather than engineer a new single molecule, Novo Nordisk paired an existing approved GLP-1 drug (semaglutide 2.4 mg) with a novel long-acting amylin analogue (cagrilintide)

Live dreams Temporary increase in cortisol or prolactin in susceptible individuals (much less common than older GHRPs) The effects reported are generally mild and temporary