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Anthem may also cover other common weight-loss medications: Saxenda (liraglutide): Often requires prior authorization Contrave (naltrexone/bupropion): Coverage varies and often needs prior authorization

Synthetic peptide impurities may include truncation sequences, deletion variants, racemized amino acids, deamidated species, and -alanine insertions

Although semaglutide improves patient-reported outcomes and exercise performance, more studies assessing incretin-based treatments to minimize clinical events in obesity-related HFpEF are required

Hongyu Qin and colleagues conducted animal and human studies to document a metabolic pathway for semaglutide to reduce inflammation from osteoarthritis