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The one consequence to be drawn from these considerations is not to treat subjects at high risk for developing medullary thyroid carcinoma based on multiple endocrine neoplasia or familial medullary thyroid carcinoma with liraglutide (according the label), and it is advisable to practice caution with other incretin-based medications as well

The tirzepatide group achieved a mean body-weight reduction of 18%, which appeared greater than that in the placebo group (45)