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When the hypothalamus is already sensitized, sudden drops or spikes in glucose function as triggers for vasomotor responses (hot flashes)

Previous studies have shown that internalization of these receptors following ligand stimulation is more pronounced in IR than IGF1R (14), and this effect is decreased in insulin-resistant obese subjects and obese type 2 diabetic patients (24)

Reduce appetite: Trigger slow digestible carbohydrate activities, which means your body gets less plasma glucose from your food and releases less sugar into your bloodstream