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This July 2024 study from Harvard Medical School and Massachusetts Eye and Ear triggered serious concerns among ophthalmologists and patients about risks that remain inadequately disclosed on current warning labels
Association between GLP-1 receptor gene polymorphisms with reward learning, anhedonia and depression diagnosis
Additionally, evaluations of data from the TriNetX network, a global clinical data repository revealed a significantly increased risk of depression, anxiety, and suicidal behavior in those patients taking GLP-1 Receptor agonists as compared with other medications for diabetes
The medication enhances glucose-dependent insulin secretion, suppresses inappropriate glucagon release, delays gastric emptying, and reduces appetite through central mechanisms
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