Pericytes also regulate the gene expression patterns of BBB-specific patterns in endothelial cells and induce polarization of astrocyte end feet [38, 39]
In a randomized trial, patients receiving tirzepatide achieved mean weight reductions of 15% to 20.9% after 52 weeks, compared to a 3.1% reduction with placebo [2]
doi: 10.3389/fmicb.2025.1535356 Received 27 November 2024 Accepted 23 June 2025 Published 09 July 2025 Volume 16 - 2025 Edited by Zhangran Chen, Xiamen University, China Reviewed by Abbas Yadegar, Shahid Beheshti University of Medical Sciences, Iran Sourish Bhattacharya, Central Salt and Marine Chemicals Research Institute (CSIR), India Updates Copyright 2025 Zhu, Fu, Olovo, Xu, Wu, Wei, Jiang and Zheng
Apr 2009;60(4):643-659