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Am J Clin Pathol 1968, 49:347-357 67

On the other hand, Fe 2 in the labile iron pool is redox-active and can act as a catalyst in the Fenton reaction [18, 19], reacting with hydrogen peroxide to produce highly reactive hydroxyl radicals, which can inflict oxidative damage on cellular components, including DNA, proteins, and cell membranes lipids, lead to the accumulation of lipid reactive oxygen species (ROS)

Clinical: 1.0% topical idebenone reduced roughness/dryness (26%), increased hydration (+37%), reduced fine lines (29%), and improved overall photodamage (+33%) in 6 weeks

B12 injections can help maintain adequate red blood cell levels, reducing the risk of developing megaloblastic anemia, a condition characterized by large and inefficient red blood cells