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Chronic elevated cortisol promotes abdominal fat storage and interferes with sleep (which further promotes weight gain)

Another amino acid, glutamine, has very little research on its possible nootropic effects, but one literature review suggests that supplementation may be able to improve mood and cognition in cases of high-altitude hypoxic stress (low levels of oxygen in your body from living in or visiting high-altitude regions).71 72 Vitamins and minerals Often affecting mood and cognition, fatigue and brain fog are highly prevalent symptoms of vitamin and mineral deficiencies

Age-related weight gain

Intense training causes microscopic muscle damage and fatigue, which can compromise future performance