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In that research, this pairing, breakdown of damaged material alongside stimulation of new matrix production, is described as a coordinated and beneficial part of tissue repair, not a harmful side effect

Aguilar-Salinas CA, Rojas R, Gmez-Prez FJ, Valles V, Ros-Torres JM, Franco A, Olaiz G, Rull JA, Seplveda J

In AWARD-10 [31], a 24-week, randomized, double-blind, placebo-controlled trial evaluating once-weekly dulaglutide (administered at either 1.5 or 0.75 mg) as add-on therapy to SGLT2is in a total of 424 patients with inadequately controlled T2DM, only one episode of severe hypoglycemia was reported throughout the study, in a patient treated with dulaglutide 0.75 mg, confirming the very low incidence of serious hypoglycemia with GLP-1RAs in combination with SGLT2is [31]

Glutathione works at the cellular level to neutralise oxidative damage