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The distal domains are stabilized in the desensitized state likely by inter-domain interactions mediated by N-glycans at Asn 247 and Asn 402 apart from other protein-protein interactions
Pancreatitis is a dangerous inflammation of the pancreas that can be fatal
It is also worth holding in mind the general clinical principle I raised earlier: if the musculoskeletal presentation of a patient with a known or suspected endocrine disorder does not fully match the history or mechanism, consider whether the endocrine condition may be contributing to the symptom picture
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