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53 Generally, the reported K m of PARP1 and CD38 for NAD + are lower than those of the sirtuins, suggesting that elevated activation of PARP1 or CD38 may limit endogenous SIRT activation by reducing NAD + content

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Its important to approach this area with appropriate calibration between enthusiasm and evidence

The paper, titled Exploring the Relationship Between Newly Defined Continuous Glucose Monitoring (CGM) Metrics and the Standard CGM Metrics in 30,000 People with Type 1 Diabetes, highlights important insights into how emerging CGM metrics relate to established standards in a large cohort