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The heterogeneity of these findings may be attributed to variations in study design, population characteristics, and the types of drug formulations used [9]

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research into the role of the gut microbiome is at an early stage and is not yet used clinically to guide treatment decisions Adherence to treatment: Missing doses or inconsistent injection timing may reduce efficacy Concurrent medicines: As a class effect, GLP-1 receptor agonists slow gastric emptying, which may affect the absorption timing of some oral medicines