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By activating both GIP and GLP-1 receptors, Mounjaro enhances insulin secretion in a glucose-dependent manner, suppresses inappropriate glucagon release, slows gastric emptying, and promotes satiety through central appetite regulation

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You can read the full article at Effect of Subcutaneous Tirzepatide vs Placebo Added to Titrated Insulin Glargine on Glycemic Control in Patients With Type 2 Diabetes: The SURPASS-5 Randomized Clinical Trial Little is known about the effects of tirzepatide, a medication that stimulates both the glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptors, when added to insulin glargine for treating type 2 diabetes