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388 To confirm the role of GLP-1 in enhancing physical endurance and the possible mechanisms involved, an in vivo AAV-mediated GLP-1 overexpression model and an in vitro siRNA-mediated AMPK knockdown model were generated

This is a huge cost burden that ultimately may stop people from accessing the medication they need and worsen health outcomes. Key insights from the new report include: More people are losing coverage: In 2025, the number of people without commercial insurance coverage for these medications surged significantly